Galleria mellonella lysozyme induces apoptotic changes in Candida albicans cells
نویسندگان
چکیده
منابع مشابه
Lactobacillus paracasei modulates the immune system of Galleria mellonella and protects against Candida albicans infection
Probiotics have been described as a potential strategy to control opportunistic infections due to their ability to stimulate the immune system. Using the non-vertebrate model host Galleria mellonella, we evaluated whether clinical isolates of Lactobacillus spp. are able to provide protection against Candida albicans infection. Among different strains of Lactobacillus paracasei, Lactobacillus rh...
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The aim of the present study was to identify Candida albicans transcription factors (TFs) involved in virulence. Although mice are considered the gold-standard model to study fungal virulence, mini-host infection models have been increasingly used. Here, barcoded TF mutants were first screened in mice by pools of strains and fungal burdens (FBs) quantified in kidneys. Mutants of unannotated gen...
متن کاملPhysical stress primes the immune response of Galleria mellonella larvae to infection by Candida albicans.
Larvae of the greater wax moth (Galleria mellonella) that had been subjected to physical stress by shaking in cupped hands for 2 min showed reduced susceptibility to infection by Candida albicans when infected 24 h after the stress event. Physically stressed larvae demonstrated an increase in haemocyte density and elevated mRNA levels of galiomicin and an inducible metalloproteinase inhibitor (...
متن کاملNew to Galleria mellonella
EditoriAL Pathogens and their respective hosts interact closely leading to the host–pathogen framework response that could result in different outcomes that range from pathogen elimination to death of the host. To improve our ability to propose new measures that promote pathogen elimination and prevent host death, we need to have a comprehensive understanding of this interaction. Generally , mo...
متن کاملCorrelation of phospholipase and proteinase production of Candida with in vivo pathogenicity in Galleria mellonella
An essential factor to the virulence of the genus Candida is the ability to produce enzymes and this may be crucial in the establishment of fungal infections. Aim: This study investigated in vitro enzymatic activities of Candida species and their virulence in an in vivo Galleria mellonella experimental model. Methods: Twenty-four clinical strains of Candida spp. isolated from the human oral cav...
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ژورنال
عنوان ژورنال: Microbiological Research
سال: 2016
ISSN: 0944-5013
DOI: 10.1016/j.micres.2016.10.003